にしても
Even if, granted that, or regardless of whether.
Readings
Even if" / "Granted that...
Acknowledges a valid reason or circumstance while emphasizing that the resulting degree or situation is still excessive or unacceptable.
Example
Granted that it's a joke, there are still things you should and shouldn't say.
Whether... or...
Connects two contrasting or similar options to assert that the outcome or rule remains unchanged regardless of the choice.
No matter (what, who, etc.)
Combines with interrogatives to indicate that a statement holds true under any circumstance, location, or condition.
Even for...
Highlights a specific person or entity to indicate that a condition applies even to them, often contrary to expectation.